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Product Description
Potent and selective inhibitor of CYP3A (IC50 = 30 nM (CYP3A4), 17 μM (CYP3A5) and 70 μM (CYP3A7).
Potent and selective inhibitor of CYP3A (IC50 = 30 nM (CYP3A4), 17 μM (CYP3A5) and 70 μM (CYP3A7).
Biovision | 2917 | PF-04981517 DataSheet
Alternate Name/Synonyms: 1-methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-(1-piperidinyl)-1-pyrrolidinyl]-1H-pyrazolo[3,4-d]pyrimidine, CYP3cide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1390637-82-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₆H₃₂N₈
Molecular Weight: 456.6
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (~20 mg/ml), DMF (~30 mg/ml), Ethanol (~2 mg/ml)
Handling: Protect from air, light and moisture
Country of Origin: USA
Tag Line: A potent and specific inhibitor of Cytochrome P450 3A
MDL Number: N/A
PubChem CID: 71315139
SMILES: CC1=CC=C(C=C1)C2=C(C=NN2C)C3=NN(C4=C3C(=NC=N4)N5CCC(C5)N6CCCCC6)C
InChi: InChI=1S/C26H32N8/c1-18-7-9-19(10-8-18)24-21(15-29-31(24)2)23-22-25(32(3)30-23)27-17-28-26(22)34-14-11-20(16-34)33-12-5-4-6-13-33/h7-10,15,17,20H,4-6,11-14,16H2,1-3H3/t20-/m0/s1
InChi Key: WDWIMDKOXZZYHH-FQEVSTJZSA-N
