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Product Description
A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.
PHT-427 is a potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor.
Biovision | 2465 | PHT-427 DataSheet
Alternate Name/Synonyms: 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 1191951-57-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₃₁N₃O₃S₂
Molecular Weight: 409.61
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (> 80 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent Akt and PDPK1 inhibitor
MDL Number: N/A
PubChem CID: 44240850
SMILES: CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2
InChi: InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
InChi Key: BYWWNRBKPCPJMG-UHFFFAOYSA-N
