Product Description
PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.
PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.
Biovision | B1668 | PIK75 DataSheet
Alternate Name/Synonyms: PIK75 , PIK75; PIK 75; PIK-75 Hydrochloride; PIK75 Hydrochloride; PIK 75 Hydrochloride; (E)-N'-((6-bromoH-imidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride; PIK-75 Hydrochloride; PIK75 Hydrochloride; PIK 75 Hydrochloride
Appearance: Solid
Formulation: N/A
CAS Number: 372196-77-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₅BrClN₅O₄S
Molecular Weight: 488.74
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: Inhibitor of PI3K isoform p110α
MDL Number: MFCD12546130
PubChem CID: 45265864
SMILES: CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)N=CC2=CN=C3N2C=C(C=C3)Br.Cl
InChi: InChI=1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
InChi Key: VOUDEIAYNKZQKM-MYHMWQFYSA-N