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Product Description
Piperine is the primary pungent alkaloid isolated from the fruit of black peppercorns. It displays a variety of therapeutic activities such as anti-oxidant, anti-inflammatory, immunomodulatory, anti-asthmatic, anti-convulsant, anti-mutagenic, antimycobacterial, anti-amoebic, and anti-cancer activities. Piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 µM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.
Piperine is the primary pungent alkaloid isolated from the fruit of black peppercorns. It displays a variety of therapeutic activities such as anti-oxidant, anti-inflammatory, immunomodulatory, anti-asthmatic, anti-convulsant, anti-mutagenic, antimycobacterial, anti-amoebic, and anti-cancer activities
Biovision | B2086 | Piperine DataSheet
Alternate Name/Synonyms: (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one; N-Piperoylpiperidin; NSC 21727; Bioperine
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 94-62-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₉NO₃
Molecular Weight: 285.354
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent antioxidant and antiinflammatory agent
MDL Number: MFCD00005839
PubChem CID: 638024
SMILES: C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3
InChi: InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChi Key: MXXWOMGUGJBKIW-YPCIICBESA-N
