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Product Description
Prostaglandin E2 (PGE2) is a primary product of arachidonic metabolism and is synthesized via the cyclooxygenase (COX) and prostaglandin synthase pathways. PGE2 production is a commonly used method for the detection of COX-1 and COX-2 modulation and prostaglandin synthases. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Regulates vertebrate haematopoietic stem cell homeostasis.
Prostaglandin E2 (PGE2) is a primary product of arachidonic metabolism and is synthesized via the cyclooxygenase (COX) and prostaglandin synthase pathways. Regulates vertebrate haematopoietic stem cell homeostasis.
Biovision | 2268 | Prostaglandin E2 DataSheet
Alternate Name/Synonyms: 9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid; PGE2; Dinoprostone
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 363-24-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₃₂O₅
Molecular Weight: 352.47
Cell-Permeable?: No
Purity: ≥98% by TLC
Solubilities: DMSO (~100 mg/ml) or EtOH (~100 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An endogenous prostanoid
MDL Number: MFCD00077861
PubChem CID: 5280360
SMILES: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
InChi: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1
InChi Key: XEYBRNLFEZDVAW-ARSRFYASSA-N
