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Product Description
Cell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.
PX-866 is a derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.
Biovision | 1965 | PX-866 DataSheet
Alternate Name/Synonyms: DJM-166; DJM-2-166
Appearance: Orange solid
Formulation: N/A
CAS Number: 502632-66-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₃₅NO₈
Molecular Weight: 525.59
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~ 25 mg/ml)
Handling: Protect from light and air
Country of Origin: USA
Tag Line: A potent PI3 Kinase inhibitor
MDL Number: MFCD07784511
PubChem CID: 9849735
SMILES: CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN(CC=C)CC=C)C4=C(C3=O)O)COC)C)C
InChi: InChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20 (32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8, 14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+,28-,29-/m0/s1
InChi Key: QIUASFSNWYMDFS-NILGECQDSA-N
