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Product Description
Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor-α (TNF-α). Displays potent anti-tumor and anti-inflammatory effects as well as modulates and potentiates host immune responses against multiple myeloma.
(R,S)-Lenalidomide is an analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor-α (TNF-α).
Biovision | 1862 | (R,S)-Lenalidomide DataSheet
Alternate Name/Synonyms: (R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 191732-72-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₃N₃O₃
Molecular Weight: 259.26
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~100 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: Tumor Necrosis Factor-α (TNF-α) inhibitor
MDL Number: MFCD07772307
PubChem CID: 216326
SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
InChi: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
InChi Key: GOTYRUGSSMKFNF-UHFFFAOYSA-N
