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Product Description
Cell-permeable. A Selective inhibitor of cAMP phosphodiesterase (PDE4) (IC₅₀ = 2.0 μM). Discriminates between two conformational states of PDE4 isoenzymes.
(R,S)-Rolipram is a selective inhibitor of cAMP phosphodiesterase (PDE4) (IC₅₀ = 2.0 μM). Discriminates between two conformational states of PDE4 isoenzymes.
Biovision | 2010 | (R,S)-Rolipram DataSheet
Alternate Name/Synonyms: 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
Appearance: White solid
Formulation: N/A
CAS Number: 61413-54-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₂₁NO₃
Molecular Weight: 275.35
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 75 mM) or EtOH (~ 75 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective PDE4 inhibitor
MDL Number: MFCD00270906
PubChem CID: 5092
SMILES: COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
InChi: InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)
InChi Key: HJORMJIFDVBMOB-UHFFFAOYSA-N
