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Product Description
Radotinib is a BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI). Also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. Displays antineoplastic activities.
Radotinib is a BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI). Also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. Displays antineoplastic activities.
Biovision | 9613 | Radotinib DataSheet
Alternate Name/Synonyms: 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide; IY-5511
Appearance: White solid
Formulation: N/A
CAS Number: 926037-48-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₇H₂₁F₃N₈O
Molecular Weight: 530.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI)
MDL Number: N/A
PubChem CID: 16063245
SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5
InChi: InChI=1S/C27H21F3N8O/c1-16-3-4-18(9-23(16)37-26-33-6-5-22(36-26)24-13-31-7-8-32-24)25(39)35-20-10-19(27(28,29)30)11-21(12-20)38-14-17(2)34-15-38/h3-15H,1-2H3,(H,35,39)(H,33,36,37)
InChi Key: DUPWHXBITIZIKZ-UHFFFAOYSA-N
