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Product Description
Retinoic acid is a metabolite of vitamin A that acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer. Retinoic acid primes embryonic stem cells to become neurons.
Retinoic acid is a metabolite of vitamin A that acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer. Retinoic acid primes embryonic stem cells to become neurons.
Biovision | 2218 | Retinoic acid DataSheet
Alternate Name/Synonyms: ATRA; Tretinoin; NSC 122758; Vitamin A Acid; all-trans Retinoic Acid; NSC 122578
Appearance: Yellow solid with an orange tinge
Formulation: N/A
CAS Number: 302-79-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₈O₂
Molecular Weight: 300.44
Cell-Permeable?: Yes
Purity: ≥98% by titration
Solubilities: DMSO (20 mg/ml) or Ethanol (0.5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A retinoic acid receptor (RAR) and the retinoid X receptor (RXR) ligand
MDL Number: MFCD00001551
PubChem CID: 444795
SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
InChi: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChi Key: SHGAZHPCJJPHSC-YCNIQYBTSA-N
