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Product Description
A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66 μM) and an aurora kinase inhibitor (IC₅₀'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound.
Reversine is a cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66 μM) and an aurora kinase inhibitor (IC₅₀'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts.
Biovision | 1851 | Reversine DataSheet
Alternate Name/Synonyms: 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Appearance: Off-white solid
Formulation: N/A
CAS Number: 656820-32-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₇N₇O
Molecular Weight: 393.49
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~7-10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An A3 adenosine receptor antagonist
MDL Number: MFCD07784513
PubChem CID: 210332
SMILES: C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
InChi: InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27)
InChi Key: ZFLJHSQHILSNCM-UHFFFAOYSA-N
![[Boc-Asp(Obzl)-Lys(z)-OtBu], Reversin 121 | BC-052](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/391598/570061/klogo__76714.1643661101__71733.1644060017.png?c=2 "[Boc-Asp(Obzl)-Lys(z)-OtBu], Reversin 121 | BC-052")
