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Product Description
Cell-permeable. A high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(Ki = 4.8 nM, IC₅₀ = 37 nM).
Ro 61-8048 is a high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(Ki = 4.8 nM, IC₅₀ = 37 nM).
Biovision | 1912 | Ro 61-8048 DataSheet
Alternate Name/Synonyms: 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Appearance: Off-white solid
Formulation: N/A
CAS Number: 199666-03-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₅N₃O₆S₂
Molecular Weight: 421.45
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (100 mM) or EtOH (10 mM)
Handling: Protect from light
Country of Origin: USA
Tag Line: An inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase
MDL Number: MFCD11040807
PubChem CID: 5282337
SMILES: COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
InChi: InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
InChi Key: NDPBMCKQJOZAQX-UHFFFAOYSA-N
