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Product Description
Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM). Displays anti-inflammatory properties.
Roflumilast is a selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.8 nM). Displays anti-inflammatory properties.
Biovision | 2675 | Roflumilast DataSheet
Alternate Name/Synonyms: 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107; BY 217; BYK 20869; Daxas
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 162401-32-3
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₄Cl₂F₂N₂O₃
Molecular Weight: 403.21
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective phosphodiesterase 4 (PDE4) inhibitor
MDL Number: MFCD00938270
PubChem CID: 449193
SMILES: C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
InChi: InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
InChi Key: MNDBXUUTURYVHR-UHFFFAOYSA-N
