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Product Description
SB 202190 is a highly selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC₅₀ values of 50 and 100 nM, respectively. At higher concentrations (10 µM), SB 202190 displays negligible effects on several other kinases including other MAP kinases (ERKs, JNKs).
SB 202190 is a highly selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC₅₀ values of 50 and 100 nM, respectively. At higher concentrations (10 µM), SB 202190 displays negligible effects on several other kinases including other MAP kinases (ERKs, JNKs).
Biovision | 2493 | SB 202190 DataSheet
Alternate Name/Synonyms: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol
Appearance: Off-white solid
Formulation: N/A
CAS Number: 152121-30-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C20H14FN3O
Molecular Weight: 331.34
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective MAP Kinase inhibitor
MDL Number: MFCD00941964
PubChem CID: 5353940
SMILES: C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
InChi: InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,23-24H
InChi Key: NJNKPVPFGLGHPA-UHFFFAOYSA-N
