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Product Description
A potent, reversible, small molecule inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. Displays anticancer properties.
SB-715992 is a potent, reversible, small molecule inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.
Biovision | 2468 | SB-715992 DataSheet
Alternate Name/Synonyms: (R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide; Ispinesib; CK0238273
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 336113-53-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₀H₃₃ClN₄O₂
Molecular Weight: 517.06
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (> 50 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, reversible, kinesin spindle protein (KSP) inhibitor
MDL Number: N/A
PubChem CID: 6851740
SMILES: CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChi: InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
InChi Key: QJZRFPJCWMNVAV-HHHXNRCGSA-N
