Product Description
SB-742457 is a highly selective 5-HT6 receptor antagonist with potential cognition, memory and learning-enhancing effects; displays >100-fold selectivity over other receptors. in anxiolytic and antidepressant-like activity. SB-742457 shows increasing pro-cognitive effects in patients with Alzheimer’s Disease (AD).
SB-742457 is a highly selective 5-HT6 receptor antagonist with potential cognition, memory and learning-enhancing effects; displays >100-fold selectivity over other receptors. in anxiolytic and antidepressant-like activity. SB-742457 shows increasing pro-cognitive effects in patients with Alzheimer’s Disease (AD).
Biovision | 9568 | SB-742457 DataSheet
Alternate Name/Synonyms: 3-(Benzenesulfonyl)-8-piperazin-1-ylquinoline; RVT-101
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 607742-69-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₉N₃O₂S
Molecular Weight: 353.44
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly selective 5-HT6 receptor antagonist
MDL Number: N/A
PubChem CID: 11256720
SMILES: C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4
InChi: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2
InChi Key: JJZFWROHYSMCMU-UHFFFAOYSA-N