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Product Description
A reversible, competitive inhibitor of IKK2 (IC₅₀ = 11.2 µM). Does not inhibit other IKK isoforms, or other kinases. Displays dose-dependent inhibition of the transcription of NK-κB dependent genes in cell culture.
SC-514 is a reversible, competitive inhibitor of IKK2 (IC₅₀ = 11.2 µM).
Biovision | 2442 | SC-514 DataSheet
Alternate Name/Synonyms: 5-(Thien-3-yl)-3-aminothiophene-2-carboxamide
Appearance: Yellow solid
Formulation: N/A
CAS Number: 354812-17-2
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₉H₈N₂OS₂
Molecular Weight: 224.3
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~25 mg/ml)
Handling: Protect from light and air
Country of Origin: USA
Tag Line: A reversible, competitive inhibitor of IKK2
MDL Number: MFCD00206459
PubChem CID: 2807869
SMILES: C1=CSC=C1C2=CC(=C(S2)C(=O)N)N
InChi: InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12)
InChi Key: BMUACLADCKCNKZ-UHFFFAOYSA-N
