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Product Description
Shikonin is a naturally occurring naphthoquinone derivative that displays anti-inflammatory and antitumor properties. Displays anti-angiogenic properties by inhibition of proliferation and migration of endothelial cells, blocking integrin αvβ3 expression,etc. Shikonin also inhibits cancer cell glycolysis by targeting tumor pyruvate kinase M2 (PKM2).
Shikonin is a naturally occurring naphthoquinone derivative that displays anti-inflammatory and antitumor properties. Displays anti-angiogenic properties by inhibition of proliferation and migration of endothelial cells, blocking integrin αvβ3 expression,etc. Shikonin also inhibits cancer cell glycolysis by targeting tumor pyruvate kinase M2 (PKM2).
Biovision | B1056 | Shikonin DataSheet
Alternate Name/Synonyms: (±)-Alkannin, (±)-Shikalkin, (±)-Shikonin, (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone
Appearance: Red to brown solid
Formulation: N/A
CAS Number: 517-89-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₆O₅
Molecular Weight: 288.3
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A pyruvate kinase M2 (PKM2) inhibitor
MDL Number: MFCD00016668
PubChem CID: 5208
SMILES: CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C
InChi: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3
InChi Key: NEZONWMXZKDMKF-UHFFFAOYSA-N
