Product Description
SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC₅₀ = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).
SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC₅₀ = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).
Biovision | B2275 | SMI-16a DataSheet
Alternate Name/Synonyms: (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione; Pim1/2 Inhibitor IV
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 587852-28-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₃NO₃S
Molecular Weight: 263.31
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases
MDL Number: N/A
PubChem CID: 4349931
SMILES: CCCOC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
InChi: InChI=1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)
InChi Key: GBWOSXZUTXXXQF-UHFFFAOYSA-N