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Product Description
Cell-permeable. A Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.
Smo Agonist, SAG is a Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.
Biovision | 1939 | Smo Agonist, SAG DataSheet
Alternate Name/Synonyms: N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane
Appearance: Off-white solid
Formulation: N/A
CAS Number: 912545-86-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₈H₂₈ClN₃OS
Molecular Weight: 490.06
Cell-Permeable?: Yes
Purity: ≥98% by NMR
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from light
Country of Origin: USA
Tag Line: A Smoothened (Smo) agonist
MDL Number: N/A
PubChem CID: N/A
SMILES: N/A
InChi: N/A
InChi Key: N/A
