Product Description
Potent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Induces apoptosis in CHO cells at 1 µM.
Staurosporine is a potent inhibitor of protein kinase C (PKC) and most other kinases, including tyrosine kinases.
Biovision | 1048 | Staurosporine DataSheet
Alternate Name/Synonyms: Antibiotic AM-2282
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 62996-74-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₈H₂₆N₄O₃
Molecular Weight: 466.53
Cell-Permeable?: Yes
Purity: >99% by TLC
Solubilities: DMSO ( 25 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A protein kinase inhibitor
MDL Number: MFCD00077402
PubChem CID: 451705
SMILES: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
InChi: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1
InChi Key: HKSZLNNOFSGOKW-HMWZOHBLSA-N