Product Description
SU-5614 is a potent and selective FLT3 (FMS-like tyrosine kinase 3) inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
SU-5614 is a potent and selective FLT3 (FMS-like tyrosine kinase 3) inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3.
Biovision | 9643 | SU-5614 DataSheet
Alternate Name/Synonyms: (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one; GK4754
Appearance: Orange solid
Formulation: N/A
CAS Number: 1055412-47-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₃ClN₂O
Molecular Weight: 272.73
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective FLT3 inhibitor.
MDL Number: MFCD08443928
PubChem CID: 6536806
SMILES: CC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
InChi: InChI=1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
InChi Key: XLBQNZICMYZIQT-GHXNOFRVSA-N