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Product Description
SU-6656 is a potent and selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). In NIH 3T3 cells, SU-6656 inhibits PDGF-/Src-driven mitogenesis and PDGF-stimulated c-Myc induction. SU-6656 in combination with radiation decrease clonogenic survival of endothelial cells.
SU-6656 is a potent and selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). In NIH 3T3 cells, SU-6656 inhibits PDGF-/Src-driven mitogenesis and PDGF-stimulated c-Myc induction. SU-6656 in combination with radiation decrease clonogenic survival of endothelial cells.
Biovision | B2334 | SU-6656 DataSheet
Alternate Name/Synonyms: (Z)-2-hydroxy-N,N-dimethyl-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-3H-indole-5-sulfonamide
Appearance: Orange brown solid
Formulation:
CAS Number: 330161-87-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₉H₂₁N₃O₃S
Molecular Weight: 371.45
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >10 mg/ml (DMSO)
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective Src tyrosine kinase inhibitor
MDL Number: MFCD10565928
PubChem CID: 5312137
SMILES: CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=O)C2=CC3=CC4=C(N3)CCCC4
InChi: InChI=1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-
InChi Key: LOGJQOUIVKBFGH-YBEGLDIGSA-N
