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Product Description
SW-033291 is a potent inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) (Ki = ~0.1 nM). It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection. SW033291 accelerates hematopoietic recovery in mice receiving bone marrow transplant and promotes tissue regeneration in mouse models of colon and liver injury.
SW-033291 is a potent inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) (Ki = ~0.1 nM). It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection. SW033291 accelerates hematopoietic recovery in mice receiving bone marrow transplant and promotes tissue regeneration in mouse models of colon and liver injury.
Biovision | 9584 | SW-033291 DataSheet
Alternate Name/Synonyms: 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine;SW033291
Appearance: White solid
Formulation: N/A
CAS Number: 459147-39-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₂₀N₂OS₃
Molecular Weight: 412.58
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent 15-PGDH (15-hydroxy prostaglandin dehydrogenase) inhibitor
MDL Number: N/A
PubChem CID: 3337839
SMILES: CCCCS(=O)C1=C(C2=C(S1)N=C(C=C2C3=CC=CC=C3)C4=CC=CS4)N
InChi: InChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
InChi Key: LCYAYKSMOVLVRL-UHFFFAOYSA-N
