Euro
USD
British Pound
NULL
Product Description
TA-01 is a potential inhibitor of Casein kinase ε(CK1ε), casein kinase 1δ (CK1δ) and mitogen activated protein kinase(MAPK) p38α with IC₅₀ of 6.4, 6.8 and 6.7 nM, respectively. It shows complete inhibition of cardiogenesis at 5 μM showing reduced expression of mesoderm markers and the pre-cardiac marker Isl-1.
TA-01 is a potential inhibitor of Casein kinase ε(CK1ε), casein kinase 1δ (CK1δ) and mitogen activated protein kinase(MAPK) p38α with IC₅₀ of 6.4, 6.8 and 6.7 nM, respectively. It shows complete inhibition of cardiogenesis at 5 μM showing reduced expression of mesoderm markers and the pre-cardiac marker Isl-1.
Biovision | B1214 | TA-01 DataSheet
Alternate Name/Synonyms: 4-(2-(2,6-Difluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Appearance: Beige Solid
Formulation: N/A
CAS Number: 1784751-18-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₁₂F₃N₃
Molecular Weight: 351.32
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO(>5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent inhibitor of Casein kinase ε(CK1ε), casein kinase 1δ (CK1δ)and mitogen activated protein kinase(MAPK) p38α
MDL Number:
PubChem CID: 91691129
SMILES: C1=CC(=C(C(=C1)F)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)F
InChi: InChI=1S/C20H12F3N3/c21-14-6-4-12(5-7-14)18-19(13-8-10-24-11-9-13)26-20(25-18)17-15(22)2-1-3-16(17)23/h1-11H,(H,25,26)
InChi Key: TWPJJJZCYVFUOA-UHFFFAOYSA-N
