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Product Description
Telaprevir is a peptidomimetic inhibitor of hepatitis C virus protease. Telaprevir inhibits the hepatitis C virus NS3-4A serine protease, blocking the viral polyprotein processing. The dose dependent process leads to decrease in viral RNA replication, decreased HCV RNA and protein levels in con1 subgenomic HCV replicon cells.
Telaprevir is a peptidomimetic inhibitor of hepatitis C virus protease. Telaprevir inhibits the hepatitis C virus NS3-4A serine protease, blocking the viral polyprotein processing. The dose dependent process leads to decrease in viral RNA replication, decreased HCV RNA and protein levels in con1 subgenomic HCV replicon cells.
Biovision | B1235 | Telaprevir DataSheet
Alternate Name/Synonyms: (3S,3aS,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
Appearance: White Solid
Formulation: N/A
CAS Number: 402957-28-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₆H₅₃N₇O₆
Molecular Weight: 679.85
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO(>100 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A hepatitis C virus protease inhibitor
MDL Number: MFCD11616089
PubChem CID: 3010818
SMILES: CCCC(C(=O)C(=O)NC1CC1)NC(=O)C2C3CCCC3CN2C(=O)C(C(C)(C)C)NC(=O)C(C4CCCCC4)NC(=O)C5=NC=CN=C5
InChi: InChI=1S/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25-,27-,28-,30+/m0/s1
InChi Key: BBAWEDCPNXPBQM-GDEBMMAJSA-N
