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Product Description
TGR-1202 (also known as RP5264), is a highly specific inhibitor of PI3Kδ, targeting the δ isoform with nanomolar potency and several-fold selectivity over the α, β, and g isoforms of PI3K.
TGR-1202 (also known as RP5264), is a highly specific inhibitor of PI3Kδ, targeting the δ isoform with nanomolar potency and several-fold selectivity over the α, β, and g isoforms of PI3K.
Biovision | B1284 | TGR-1202 DataSheet
Alternate Name/Synonyms: (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one; RP5264
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1532533-67-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₁H₂₄F₃NO₃
Molecular Weight: 571.56
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly specific PI3Kδ inhibitor
MDL Number: N/A
PubChem CID: 72950888
SMILES: C(C)OC1=C(C=C(C=C1)C2=NN(C3=C2C(=NC=N3)N)C(C)C4=C(C(=O)C5=C(O4)C=CC(=C5)F)C6=CC(=CC=C6)F)F
InChi: InChI=1S/C31H24F3N5O3/c1-15(2)41-24-9-7-18(12-22(24)34)27-26-30(35)36-14-37-31(26)39(38-27)16(3)29-25(17-5-4-6-19(32)11-17)28(40)21-13-20(33)8-10-23(21)42-29/h4-16H,1-3H3,(H2,35,36,37)/t16-/m0/s1
InChi Key: IUVCFHHAEHNCFT-INIZCTEOSA-N
