Product Description
Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC₅₀ = 3.02 µg/ml) and DNA gyrase (IC₅₀ = 7.13 µg/ml). Displays potent activity against gram-positive and gram-negative bacteria.
Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC₅₀ = 3.02 µg/ml) and DNA gyrase (IC₅₀ = 7.13 µg/ml). Displays potent activity against gram-positive and gram-negative bacteria.
Biovision | B1565 | Trovafloxacin mesylate DataSheet
Alternate Name/Synonyms: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate; CP 99219
Appearance: White solid
Formulation: N/A
CAS Number: 147059-75-4
Structure Available?: N/A
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₀H₁₅F₃N₄O₃.CH₃SO₃H
Molecular Weight: 512.46
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (40 mg/ml) or H₂O (>20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A broad-spectrum fluoroquinolone antibiotic
MDL Number: MFCD00913361
PubChem CID: 62960
SMILES: CS(=O)(=O)O.C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F
InChi: InChI=1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16?;
InChi Key: DYNZICQDCVYXFW-GIPYJWDTSA-N