Euro
USD
British Pound
NULL
Product Description
Zanamivir is a potent and selective inhibitor of influenza A and B virus neuraminidases with IC₅₀ values of 0.95 nM and 2.7 nM, respectively. It interacts with a group of amino acids in the active site of neuraminidase, that are conserved in all influenza A and B strains. Zanamivir blocks the action of neuraminidase, which blocks the cleavage of sialic acid on the cell receptors, thus preventing release and spread of the newly formed virions.
Zanamivir is a potent and selective inhibitor of influenza A and B virus neuraminidases with IC₅₀ values of 0.95 nM and 2.7 nM, respectively. It interacts with a group of amino acids in the active site of neuraminidase, that are conserved in all influenza A and B strains. Zanamivir blocks the action of neuraminidase, which blocks the cleavage of sialic acid on the cell receptors, thus preventing release and spread of the newly formed virions.
Biovision | B1900 | Zanamivir DataSheet
Alternate Name/Synonyms: (2R,3R,4S)-3-acetamido-4-(diaminomethylideneamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Appearance: White solid
Formulation: N/A
CAS Number: 139110-80-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₂₀N₄O7
Molecular Weight: 332.31
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective inhibitor of influenza A and B virus neuraminidases
MDL Number: MFCD00866966
PubChem CID: 60855
SMILES: CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
InChi: InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
InChi Key: ARAIBEBZBOPLMB-UFGQHTETSA-N
