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Product Description
ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC₅₀s = 0.42 and 0.95 µM for α1β1γ1 and α2β1γ1, respectively. Inhibits dephosphorylation of AMPK Thr-172 by PP2Cα. Stimulates glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio.
ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC₅₀s = 0.42 and 0.95 µM for α1β1γ1 and α2β1γ1, respectively. Inhibits dephosphorylation of AMPK Thr-172 by PP2Cα. Stimulates glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio.
Biovision | B2034 | ZLN024 hydrochloride DataSheet
Alternate Name/Synonyms: 2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]pyrimidine hydrochloride
Appearance: White solid
Formulation: N/A
CAS Number: 723249-01-2 (Free base)
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₃BrN₂OS.HCl
Molecular Weight: 361.69
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An allosteric AMPK activator
MDL Number: N/A
PubChem CID: 91654626
SMILES: CC1=CC(=C(C=C1)OCCSC2=NC=CC=N2)Br.Cl
InChi: InChI=1S/C13H13BrN2OS.ClH/c1-10-3-4-12(11(14)9-10)17-7-8-18-13-15-5-2-6-16-13;/h2-6,9H,7-8H2,1H3;1H
InChi Key: MMQCYIMDROWWFE-UHFFFAOYSA-N
