Euro
USD
British Pound
NULL
Product Description
Acetyl-Coenzyme A acetyltransferase 2 (ACAT2) is an enzyme involved in lipid metabolism. Patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Biovision | 4910 | ACAT-2 human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2.
Alternates names: Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2, Sterol O-acyltransferase 2, Acyl-coenzyme A:cholesterol acyltransferase 2, Cholesterol acyltransferase 2
Taglines: An enzyme participating in lipid metabolism
NCBI Gene ID #: 16846
NCBI Gene Symbol: LEP
Gene Source: Human
Accession #: P41160
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined in an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16.2 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered solution (1 mg/ml) in 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
Reconstitution Instructions: Reconstitute in 10 mM HCl to a concentration of 1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A
