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Product Description
AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications. It has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer.
Biovision | 6339 | AKR1B10 human recombinant DataSheet
Biomolecule/Target: AKR1B10
Synonyms: Aldo-keto reductase family 1, member B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS.
Alternates names: Aldo-keto reductase family 1, member B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS.
Taglines: Involved in in the detoxification of aldehydes and ketones
NCBI Gene ID #: 20315
NCBI Gene Symbol: SDF1B
Gene Source: Human
Accession #: P40224
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50-100 ng/ml.
Results: ~100 mU/mg
Binding Capacity: N/A
Unit Definition: One unit is the amount of enzyme that oxidizes 1.0 µmole of NADPH to NADP+ per min. at pH 7.5 at 25°C.
Molecular Weight: 8.5 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Amino acid sequence: N/A
