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Product Description
BAIAP2 is a ubiquitous regulator of the actin cytoskeleton. Controlled by the Rho-family GTPases BAIAP2 facilitates filopodia development. BAIAP2 is expressed in the cytoplasm and binds small membrane-bound G-proteins to cytoplasmic effector proteins and operates as an insulin receptor tyrosine kinase substrate. BAIAP2 proposes a part for insulin in the central nervous system and was identified as interacting with the dentatorubral pallidoluysian atrophy gene, which is related to an autosomal dominant neurodegenerative disease.
Biovision | P1030 | BAIAP2 Human recombinant DataSheet
Biomolecule/Target: BAIAP2
Synonyms: Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53kDa, FLAF3, IRS-58, IRSp53/58, IRSP53.
Alternates names: Small inducible cytokine A19, CCL19, Macrophage inflammatory protein 3 , MIP-3- , EBI1-ligand chemokine, ELC, chemokine exodus-3, CK -11, chemokine (C-C motif) ligand 19, CKb11, MIP3B, MIP-3b, SCYA19, MGC34433, Beta-chemokine exodus-3, CK beta-11, Epstein-Barr virus-induced molecule 1 ligand chemokine
Taglines: N/A
NCBI Gene ID #: 6363
NCBI Gene Symbol: CCL19
Gene Source: Human
Accession #: Q99731
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 99%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human T cells using a concentration range of 10-50 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 8.8 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: In 20mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 1mM DTT and 30% glycerol.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A
