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Product Description
Carbonic anhydrase 3 (CA3) is also known as Carbonate dehydratase III, Carbonic anhydrase III, which belongs to the alpha-carbonic anhydrase family. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The catalytic activity of carbonic anhydrase 3 is activated by proton donors such as imidazole and the dipeptide histidylhistidine and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.
Biovision | 7833 | Carbonic Anhydrase 3 human recombinant DataSheet
Biomolecule/Target: Carbonic Anhydrase 3
Synonyms: CA3, Carbonic anhydrase 3
Alternates names: Fibroblast growth factor 19
Taglines: Catalyzes the reversible hydration of carbon dioxide
NCBI Gene ID #: 9965
NCBI Gene Symbol: FGF19
Gene Source: Human
Accession #: NM_005117
Recombinant: Yes
Source: E. coli.
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <1 EU/g by LAL method
Activity (Specifications/test method): Measured by its esterase activity. The specific activity is >1 pmol/min/µg.
Biological activity: Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED for this effect is 50-200 ng/ml.
Results: The specific activity is >1 pmol/min/µg.
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 21.8 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1 to 1.0 µg/µl. This solution can then be diluted into other aqueous buffers
Amino acid sequence: N/A
