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Product Description
CD226 is a 65 kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation. Recombinant human CD226 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Biovision | 7310 | CD226 human recombinant DataSheet
Biomolecule/Target: CD226
Synonyms: CD226 antigen, DNAM-1, DNAM1, PTA1, TLiSA1
Alternates names: CD226 antigen, DNAM-1, DNAM1, PTA1, TLiSA1
Taglines: Mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells
NCBI Gene ID #: 6343
NCBI Gene Symbol: SCT
Gene Source: Human
Accession #: P09683
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 microgram of protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 29.4 kDa (259 aa, 19-254 aa + His tag), confirmed by MALDI-TOF.
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNST MASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QSDSFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL LTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNQYTLFVA
