Euro
USD
British Pound
NULL
Product Description
FGF-16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues.
Biovision | 7149 | FGF-16 human recombinant DataSheet
Biomolecule/Target: FGF-16
Synonyms: Fibroblast Growth Factor-16, FGFG
Alternates names: Vascular Endothelial Growth Factor-B, VEGFB, VEGF-related factor
Taglines: Promotes cellular proliferation and differentiation
NCBI Gene ID #: 7423
NCBI Gene Symbol: VEGFB
Gene Source: Human
Accession #: P49765
Recombinant: Yes
Source: E. coli.
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).
Activity (Specifications/test method): Determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is 0.5 ng/ml corresponding to a specific activity of 2 x 10^6 units/mg.
Biological activity: Per researchers feedback, the protein is biologically active as determined by the dose-dependent stimulation of the proliferation of human mbilical vein endothelial cells (HUVEC) in the presence of human VEGF165. The expected ED for this effect is 0.5-5.0 g/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 19.63 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Tris, pH 9.0, 0.1 M L-Arginine and 0.4 mM DTT.
Reconstitution Instructions: Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
Amino acid sequence: N/A
