Product Description
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cells cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.
Biovision | P1364 | GFAP Human Recombinant DataSheet
Biomolecule/Target: GFAP
Synonyms: Glial Fibrillary Acidic Protein, GFAP
Alternates names: Glial Fibrillary Acidic Protein, GFAP
Taglines: A class-III intermediate filament that distinguishes astrocytes from other glial cells during the development of the central nervous system
NCBI Gene ID #: 2255
NCBI Gene Symbol: FGF-10
Gene Source: Human
Accession #: O15520
Recombinant: Yes
Source: E.coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <1 EU/g by LAL method
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: N/A
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Amino acid sequence: MGSSHHHHHHSSGLVPRGSHMLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM