Product Description
GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and interCellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Human Recombinant GHBP expressed from E. coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 28.1 kDa. GHBP is purified by proprietary chromatographic techniques.
Biovision | 4972 | GHBP human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: GHR, GHBP, GH receptor, Somatotropin receptor
Alternates names: Apolipoprotein E4, APOE, apolipoprotein, apolipoproteins
Taglines: A carrier protein for growth hormone
NCBI Gene ID #:
NCBI Gene Symbol:
Gene Source: Human
Accession #:
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 34.4 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: GHBP was lyophilized from a concentrated (1 mg/ml) solution with 0.0045 mM NaHCO.
Reconstitution Instructions: Reconstitute in dHO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A