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Product Description
GPNMB Glycoprotein Nmb Human Recombinant Protein
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Size 20ug
Background GPNMB Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 476 amino acids (22-474) and having a molecular mass of 53.2 kDa.
GPNMB is fused to a 23 amino acid His-tag at N-terminus & purified by propr
GPNMB is fused to a 23 amino acid His-tag at N-terminus & purified by propr
Source E. Coli
Gene name GPNMB
Contents The GPNMB solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Form Sterile Filtered colorless solution.
Purification Greater than 85.0% as determined by SDS-PAGE.
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms Transmembrane glycoprotein NMB;Transmembrane glycoprotein HGFIN;GPNMB;HGFIN, NMB;UNQ1725/PRO9925;
Subcellular localization Cell membrane; Single-pass type I membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Detected at the cell surface in different types of cancers cells, including glioblastoma multiforme cell
Tissue specificity Up-regulated in various cancer cells, including in glioblastoma multiforme. Expressed in many melanoma cells, as well as in tissue macrophages, including liver Kuppfer cells and lung alveolar macrophages, in podocytes and in some cells of the ciliary
Uniprot ID Q14956
Other Size 5ug, 20ug, 1mg, Please contact us for more details
