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Product Description
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Biovision | P1073 | Human CellExp B7-H3 / CD276 Mouse recombinant DataSheet
Biomolecule/Target: CD276
Synonyms: B7-H3, CD276, B7 homolog 3
Alternates names: Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)
Taglines: Regulate the T-cell-mediated immune response and a protective role in tumor cells by inhibiting natural-killer mediated cell lysis. Marker for detection of neuroblastoma cells.
NCBI Gene ID #: 5054
NCBI Gene Symbol: SERPINE1
Gene Source: Mouse
Accession #: P05121
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU/g
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: N/A
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized Recombinant Human SERPIN E1 in PBS not less than 100g/ml, which can then be further diluted to other aqueous solutions.
Amino acid sequence: N/A
