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Product Description
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Biovision | 9237 | Human CellExp CD28 Human recombinant DataSheet
Biomolecule/Target: CD28
Synonyms: CD28, Tp44
Alternates names: Collagen alpha-1(XVIII) chain, Endostatin-XV, Related to endostatin, Restin
Taglines: T-cell-specific surface glycoprotein CD28
NCBI Gene ID #: 80781
NCBI Gene Symbol: COL18A1
Gene Source: Human
Accession #: P39060
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 92%
Assay #2: N/A
Endotoxin Level: < 1 EU/g
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: N/A
Results: N/A
Binding Capacity: Immobilized Human B7-1, His Tag at 20g/ml, can bind Human CD28, Fc Tag with a linear of 0.2-20 g/ml and Human B7-2, His Tag at 2g/ml, can bind Human CD28, Fc Tag with a linear of 0.01-5 g/ml
Unit Definition: N/A
Molecular Weight: 20.5 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4.
Reconstitution Instructions: Reconstitute with sterile dHO to a concentration 1.0 mg/ml, aliquot and store at below 20°C. Avoid freeze-thaw cycles.
Amino acid sequence: N/A
