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Product Description
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Biovision | P1076 | Human CellExp CD47 rat recombinant DataSheet
Biomolecule/Target: CD47
Synonyms: CD47, MER6, IAP, OA3
Alternates names: Growth hormone 1, Somatotropin, Pituitary growth hormone
Taglines: Plays a role in cell adhesion modulation of integrins
NCBI Gene ID #: 2688
NCBI Gene Symbol: SOMA
Gene Source: Rat
Accession #: P01241
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU/g
Activity (Specifications/test method): N/A
Biological activity: BioVision's pituitary Growth Hormone is fully biologically active when compared to World Health Organization (WHO) reference standard.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 22.367 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized hGH in 10 mM sodium phosphate buffer (pH 8.0) or 10 mM NH4HCO3 (pH 8.0). The solution can then be further diluted to other aqueous solutions. When diluting to below 10 ug/ml, the diluted solution should contain carrier protein (BSA or others) to avoid non-specific absorption of the hGH to plastic tubes.
Amino acid sequence: N/A
