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Product Description
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor- converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
Biovision | P1166 | Human CellExp DLK1 Human Recombinant DataSheet
Biomolecule/Target: DLK1
Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Alternates names: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Taglines: Plays role in neuroendocrine differentiation.
NCBI Gene ID #: 3479
NCBI Gene Symbol: IGF1A
Gene Source: Human
Accession #: P01343
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/g
Activity (Specifications/test method): Measured by inhibition of adipogenesis of 3T3L-1 cells
Biological activity: Inhibits adipogenesis of 3T3L-1 cells
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 65 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from PBS + 0.02 % CHAPS
Reconstitution Instructions: Reconstitute with 100 µl sterile water.
Amino acid sequence: N/A
