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Product Description
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Biovision | P1337 | Human CellExp EGFR/ErbB1 Fc Tag Human Recombinant DataSheet
Biomolecule/Target: EGFR
Synonyms: EGFR, ERBB, ERBB1, HER1, PIG61, mENA
Alternates names: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin homolog, PTEN, MMAC1, TEP1, BZS, MHAM, PTEN1, 10q23del,
Taglines: A cell-surface receptor for members of the EGF-family of extracellular protein ligands.
NCBI Gene ID #: 5728
NCBI Gene Symbol: PTEN
Gene Source: Human
Accession #: P60484
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/g
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: A Phosphatase specific activity of 400 nmol/min/mg was determined using the substrate phosphatidylinositol (3,4,5) triphosphate at a final concentration of 125 M in 20 mM Tris, pH 7.5, 150 mM NaCl, 50 M MgCl2, 0.05 % Tween-20, 0.2 % 2-mercaptoethanol.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 80.0 kDa (GST tagged)
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
