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Product Description
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Biovision | 9231 | Human CellExp GITR / TNFRSF18 Human recombinant DataSheet
Biomolecule/Target: GITR
Synonyms: AITR, GITR, TNFRSF18, CD357
Alternates names: C-reactive protein, CRP, PTX1, MGC88244, MGC149895, Cysteine-rich protein 2, Protein ESP1
Taglines: Tumor necrosis factor receptor superfamily member 18
NCBI Gene ID #: 1401
NCBI Gene Symbol: CRP
Gene Source: Human
Accession #: P02741
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 92%
Assay #2: N/A
Endotoxin Level: < 1 EU/g
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: N/A
Results: N/A
Binding Capacity: Immobilized Human GITR/TNFRSF18, His Tag at 2 µg/mL (100 µL/well) can bind r-Human GITR Ligand /TNFSF18 with a linear range of 0.8-25 ng/mL.
Unit Definition: N/A
Molecular Weight: 115.0 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
