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Product Description
Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5- mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
Biovision | P1268 | Human CellExp HDAC5 Catalytic Domain Human Recombinant Active DataSheet
Biomolecule/Target: HDAC5
Synonyms: HDAC5, HD5, Histone Deacetylase 5
Alternates names: HDAC5, HD5, Histone Deacetylase 5, Antigen NY-CO-9, KIAA0600
Taglines: Key epigenetic regulator
NCBI Gene ID #: 3552
NCBI Gene Symbol: IL1A
Gene Source: Human
Accession #: P01583
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGEs: 98%
Assay: SEC
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): Deacetylation activity was determined using the Boc-K(TFA)-AMC substrate.
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 45 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: In 30 mM HEPES, 140 mM NaCl, 10 mM KCl, 3% glycerol, 0.25 mM TCEP, pH 7.6
Reconstitution Instructions: N/A
Amino acid sequence: N/A
