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Product Description
Interleukin-12 (IL-12) is an important mediator of cellular-immunity produced by dendritic cells, macrophages and B cells when stimulated with antigen. IL-12 is involved in differentiating precursor helper T cells to Th1 and/or Th2 subtypes and promotes the production of IFN gamma and TNF alpha. Mouse IL-12 is active on human and mouse cells. Recombinant mouse IL-12 is a glycosylated, disulfide-linked heterodimer. It is containing one p35 subunit (35 kDa) and one p40 subunit (40 kDa), with a total of 506 amino acids and a molecular weight of approximately 70 kDa.
Biovision | 4719 | Human CellExp IL-12 Mouse Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: NKSF, CLMF
Alternates names: HSP-40, HSP40, DnaJ, DNAJB1, HSPF1, Hdj1, DnaJ homolog subfamily B member 1, Heat shock 40 kDa protein 1, Heat shock protein 40, DnaJ protein homolog 1, HDJ-1, Sis1.
Taglines: A T cell-stimulating factor
NCBI Gene ID #: 3337
NCBI Gene Symbol: DNJB1
Gene Source: Human
Accession #: P25685
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: <0.1 EU/g purified protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: N/A
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Recombinant mouse IL-12 is lyophilized from 0.5 x PBS, pH 7.5.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
