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Product Description
IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor (IL10RB) and interleukin 28 receptor . IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumor activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues.
Biovision | 6473 | Human CellExp IL-29 Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Human Cellexp Human Recombinant IL-29
Alternates names: Hsc70-interacting protein, Suppression of tumorigenicity 13 protein, Putative tumor suppressor ST13, FAM10A1, Progesterone receptor-associated p48 protein, Renal carcinoma antigen NY-REN-33
Taglines: A cytokine mediating adaptive immune response
NCBI Gene ID #: 6767
NCBI Gene Symbol: ST13
Gene Source: Human
Accession #: P50502
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 99%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 g of protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 43 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized in PBS.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
