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Product Description
Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.
Biovision | P1203 | Human CellExp Integrin alpha 6 beta 1 Heterodimer Human Recombinant DataSheet
Biomolecule/Target: ITGA6, ITGB1
Synonyms: Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6
Alternates names: Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt, PBEF
Taglines: Hetrodimer integrin (alpha 6 beta 1) negatively regulate erbB2/HER2 signaling
NCBI Gene ID #: 297508
NCBI Gene Symbol: NAMPT
Gene Source: Rat
Accession #: Q80Z29
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/g
Activity (Specifications/test method):
Biological activity: Amino acids 1 to 491 (per UniProt Q80Z29)
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 53.0 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Reconstitution Instructions: Reconstitute in PBS to the concentration of 0.1-1 mg/ml.
Amino acid sequence: Amino acids 1 to 491 (per UniProt Q80Z29)
