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Product Description
Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.
Biovision | P1111 | Human CellExp LTBR /TNFRSF3 Human recombinant DataSheet
Biomolecule/Target: LTBR
Synonyms: LTBR, D12S370, TNFCR, TNFR3, TNFRSF3, TNFRIII
Alternates names: HDL
Taglines: Promotes apoptosis via TRAF3 and TRAF5
NCBI Gene ID #: 3069
NCBI Gene Symbol: HDLBP
Gene Source: N/A
Accession #: Q00341
Recombinant: Yes
Source: Human plasma
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU/g
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 175.0-350.0 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: N/A
Amino acid sequence: N/A
